The largest win involves providing the £35.4m first phase of a four-phase development at Devon’s Road to initially build 259 mixed-tenure homes.
The works also include 1585 sq metres of commercial space, associated external works and landscaping.
The second project involves the redevelopment of the former Plaistow Hospital site in Newham to celebrate Peabody’s 150th year.
The £24.9m scheme will see construction of 168 mixed tenure homes, and extends to the restoration of historic hospital buildings and creation of new-build homes at the site.
Galliford Try Chief Executive Greg Fitzgerald said: “We are delighted to have once again demonstrated the strength of our offering in London as an affordable housing contractor.
“We look forward to working with Peabody to realise their vision for these two major schemes in East London.”