The project will deliver a new 19,000 sq metre clinical building as well as a new front entrance and welcome area for entire hospital.

During the construction phase Sisk will employ over 500 people on site hiring 37 apprentices and creating over 20 work placements for local students.

Sisk has digitally built the project in 4D before beginning on site and the project is fully Building Safety Act (BSA) compliant – the first hospital in UK to go through the BSA process.

Construction is forecast to be complete in late 2028.

Ger Hayes, Managing Director, Sisk said: “It’s an incredible honour to be entrusted with building the new Children’s Cancer Centre at Great Ormond Street Hospital.

“We’re making significant progress in the healthcare sector both in Ireland and the UK and we fully appreciate that Great Ormond Street Hospital is one of the world’s leading children’s healthcare providers. As a family-owned business, we take immense pride in creating lasting legacies within the communities we serve and we are fully motivated to deliver a best-in-class cancer centre for GOSH and the families they support.”

Mat Shaw, Chief Executive of GOSH said: “I am delighted that we are now in contract with Sisk and building work on our fantastic new Children’s Cancer Centre is underway. Reflecting our ambition to put the child first and always, the CCC will help our staff be their best and enable children to play, learn and be with their families even while at hospital.”

GOSH and Sisk are working hard to limit the impacts of the development on the local community and families who are coming to the hospital.

Sisk is using a range of different methods to limit the transmission of dust, noise and vibrations. This includes wrapping the frontage building in sheeting and carefully dismantling it section by section, with waste materials contained before being removed from the site to be recycled or reused.