The firm will work as part of the SPACE consortium, which includes Davis Langdon Investments and Fulcrum Infrastructure Group, as development partner with a host of public procurers under the hub framework.
The hub initiative has similarities with the LIFT and BSF programmes in England.
SPACE will team up with the South East hub territory board, councils, NHS health boards and the emergency services to deliver a whole swathe of building projects.
The arrangement will see Galliford Try deliver projects through all stages from strategic planning through to project delivery, funding and facilities management via an integrated supply chain.
The first hub project, to get underway later this year, is the design and build of a new library and community joint facility in west Edinburgh with an initial capital investment of £5.7m.
This is the first of several hub schemes being piloted by the Scottish Futures Trust to pursue value for money in infrastructure investment.
Greg Fitzgerald, chief executive of Galliford Try, said: “We are delighted to have reached an agreement on this significant partnership with the South East hub Territory Partnering Board in Scotland.”