Work is due to start on the 2,200 sq m building shortly and is scheduled for completion in February 2012.
The centre will effectively double available research space with new laboratories and a biobank capable of storing samples from up to 100,000 individuals.
Nick Seddon, operations manager at Morgan Sindall in Nottingham, said: “This is the second major project we’ve been awarded from the University of Leicester.
“The CRC will further advance Leicester’s world-class reputation as a centre of excellence in cardiovascular science and we’re delighted to be involved in the delivery of such a key facility.”
Steve O’Connor, director of development at the University, adds: “The University has committed over £8 million of its scarce capital resources to this major project and has launched an appeal to raise over £4m to complete and equip the CRC building.”