The builder, in joint venture with social landlord Home Group, will form a regeneration partnership with Gateshead Council to build a mix of 2,400 affordable and private sale homes across 19 sites in the city.
All homes will achieve Level 4 of the Code for Sustainable Homes and will exceed Homes & Communities Agency space standards.
The Evolution Gateshead consortium is due to start work following financial close later this year with the development programme phased to complete by 2026.
Galliford Try Chief Executive, Greg Fitzgerald said: “I am delighted that Galliford Try will be working with Gateshead Council on the transformation of communities across Gateshead.
“We look forward to using our expertise in creating quality, sustainable housing on one of the UK’s largest regeneration projects.”