The scheme is the first phase of the Council’s 25-year masterplan for the regeneration of the town centre and waterfront area.
Development plans for the six-hectare Bridge Street site encompass the construction of shops, a cinema, a food-store, a cultural centre hotel and new council offices.
Work, which is subject to planning permission, is expected to begin in 2013.
The first phase of the scheme will be the construction of the new market alongside the existing structure, shops and restaurants.
Paul Smith, Chief Executive of Morgan Sindall Group plc, said: “Muse’s appointment as Warrington Borough Council’s development partner demonstrates its ability to continue to win and deliver complex, long-term regeneration partnership projects despite a challenging environment for urban regeneration.
“This is one of the largest planned regeneration schemes in the North West. We look forward to working alongside the Council in delivering this exciting project that is set to transform Warrington’s town centre.”
The deal is another coup for Muse which has won the role as development partner with Bournemouth and Southampton councils for huge regeneration plans in the last six months.