The 5-mile section of guided busway will run through a disused rail corridor between Leigh town centre and Newearth Road, Ellenbrook close to the A580.
Construction works on the project are expected to cost around £30m.
Ultimately the £78m scheme will link Leigh, Tyldesley, Ellenbrook, Salford and Manchester.
The 5-mile section will be on the special guided ‘tracks’ – completely off the main highway – and another 8.5-mile stretch will be along a new bus-only lane.
Interested firms have until 8 November to return PQQs, which can be found on the e-portal know as the Chest: https://www.thechest.nwce.gov.uk/procontract/supplier.nsf/frm_home?openForm