The centre in Aintree was originally set-up by first Big Brother winner Craig Phillips.
But current owners, Newcastle based National Construction Academy, are now in talks about shutting down the Aintree centre later this month.
Colin Stott, director of the National Construction Academy, told the Liverpool Echo: “The North West was particularly hit by public spending cuts and recent forecasts show the construction industry will see a slow recovery through to 2016.
“It is for this reason that we have had no option but to enter into consultation with staff regarding the proposed closure of our construction academy in Aintree.
“This was an extremely difficult decision and follows three years of hard work trying to make the centre work for the benefit of our staff, learners and the community.”
The Aintree centre currently trains around 80 apprentices each year.
National Construction Academy also has training centres in Newcastle, Nottingham and Leicester.