The scope also includes commercial units in three retained art deco buildings.
Willmott Dixon is now building up a strong track record for private sale homes.
Tim Carpenter, managing director for Willmott Dixon Housing, said: “Willmott Dixon and ISIS Waterside Regeneration have a shared vision of sustainable development.
“At Brentford, the scheme will benefit from a range of measures to use sustainable energy, including district heating, green roofs, roof top allotments and PV panels. In addition, improvements will be made to the moorings available to maximise the benefits of waterside living.”
Manchester-based ISIS Waterside Regeneration is a joint venture between the Canals and River Trust (formerly British Waterways) and Muse Developments.
Brentford Lock West ranks as their third major development, building on successes in Manchester and Leeds.