Construction on the derelict seven acre site is now scheduled to start in September.
The scheme will include the 80,000 sq ft Morrisons alongside 183 private residential units, over 50,000 sq ft of retail and restaurant space, new public realm and a primary school.
Michael Marx, CEO, Development Securities said: “We are very pleased to have secured planning at 399 Edgware Road, a scheme that demonstrates our strategy of creating value through the regeneration of redundant and undervalued real estate.
“It has been a priority for us for several years to unlock cash from our non-income producing legacy assets and the progress announced today is a significant step forward in this regard.
“We look forward to announcing positive news concerning the funding and delivery of this scheme in the near-term.”