The contract let under the ProCure 21+ framework is valued at over £100m.
As principal supply chain partner Kier will start work on the first project in July with the overall programme of works running until at least 2018.
The programme will include refurbishment, extension and new build projects, ranging in value from £1m to £20m.
Kier’s work will support the integration of health and care services at City General Hospital in Stoke and Stafford Hospital.
Haydn Mursell, finance director, said:”Over the last 11 years, we have secured over 130 projects through ProCure 21 and ProCure 21+, worth over £1.1bn to the Group.
“Today’s announcement brings the total new awards to Kier under frameworks to over £400m since 31 December 2013.”