Work will see the modernisation of 18,000 sq. metres of office space to provide a new home for over 1,600 staff.
Education civil servants will occupy the building from 2017. It was formerly home to the Foreign Office.
Mace will be working with BDP as lead designer and Hoare Lea.
Refurbishment work is set to start late in 2015 following a design procurement process.
Mace Director, Philip Worley, said: “I’m delighted that Mace has been appointed to work with the Department for Education on this important project to refurbish Old Admiralty Building.
“Mace has extensive experience of estate rationalisation and office redevelopment in the public sector, we are looking forward to the challenge and will ensure the successful delivery of this modernisation programme.”