Developers Stoford and Liberty Property Trust said work will start soon by the local firm building the first two units on the 90-acre site.
The park, just off junction 6 of the M5, will provide up to 1.5m sq ft of accommodation in a range of high quality business units.
They have been designed for a variety of employment uses to include technology, manufacturing, industrial and warehousing.
Liberty Property Trust and Stoford were granted detailed planning permission by Wychavon District Council in July for units of 160,000 sq ft and 45,000 sq ft – the first to be built at Worcester Six.
Work on the £10m infrastructure package for the park is making good progress with the upgrade to Pershore Lane now complete.
Utilities for the site, including gas, electricity and water have been installed by civil engineering specialist McPhillips, which tunneled under the M5 to connect the site to services.
Stoford director, Gerard Ludlow, said: “With the appointment of Benniman as construction partner, Worcester Six is on track to start construction this month, completing in Q2 2017.
“As the first large-scale development in Worcester for more than 10 years, we’re seeing plenty of interest in the park and are confident our speculative developments won’t be on the market for long.”
Steven Smith, managing director at Benniman, said: “We are proud to be associated with this prestigious scheme within the local area and look forward to working with Stoford and Liberty to deliver the initial phase of the development project.”