The 16-storey block will provide around 200 flats for private renters at the Longley Industrial Estate.
Legal & General, which entered the BTR sector in 2016, now has 11 schemes in operation or development across the UK, delivering 3,700 homes.
Situated between New England Street and Elder Place, the Longley Place development has been designed by EPR Architects, with Hoare Lea delivering building services and Aecom structural design.
Dan Batterton, head of build to rent at LGIM Real Assets, said: “The UK needs urban centres that are fit for purpose and can support a creative and sustainable community like Brighton. We are pleased to be bringing the BTR concept to the city, demonstrating that renting can be an aspirational choice and supporting the workforce with the quality homes they deserve.”