The developer has assembled the 3.5-acre site, which occupies a prominent position off Upper Trinity Street and Adderley Street, from five individual landowners.
It is now preparing to submit a planning application in March.
The Upper Trinity Street scheme of around eight buildings, one rising to up to 35-storeys, will consist of 1,100 flats, a 120-bedroom hotel and commercial and shopping space.
Damian Flood, CEO at Cole Waterhouse, said: “We are working closely with the Council and Digbeth’s existing community to create a scheme that enhances its surroundings in the spirit of Digbeth and builds on the success of existing redevelopments in the area, notably The Custard Factory.
“We have spent the last year and a half understanding Digbeth, its community and culture, and we are incredibly excited about what we can deliver here.”
Subject to planning approval the developer aims to start construction work next year.