A spokesman said: “In light of current market conditions, News International has decided not to proceed with re-modelling the Wapping site.”
The news organisation hopes to attract developers looking for a major housing site in the Capital.
News International came close to selling the 15-acre site three years ago for around £200m to property developer Marcus Cooper, but a deal was scuppered by the property collapse.
Most staff have already moved to offices in the adjacent 550,000 sq ft Thomas More Square complex, owned by property company Land Securities. News International said the remainder will be relocated by the end of this year.