Maintenance and stabling facilities are being extended to handle a new fleet of DLR trains.
The works will be packaged into several contracts.
Earliest work packages include a £5m design and build substation upgrade and £4m-£7m of Southern Sidings projects.
This involves three new stabling sidings and seven new switches and crossings units.
These are to be completed before the larger Northern Siding package worth £25m-£40m begins.
Northern Sidings works involve building a new carriage wash, extension and modification to existing track, and the creation and modification of new stabling sidings.
The largest project worth up to £45m involves the design, and fit out of the new maintenance facility and track connections. This will be built adjacent to the Northern Sidings and is one of the final packages to be delivered.
An official contract notice is due to be published on 18 February. More information is available by email from Transport from London.