The 100,000 sq ft project was hotly contested with national contractors Bam, Galliford Try, Kier and Sir Robert McAlpine all chasing the job.
The Pontio will house a theatre, cinema, restaurant, bars, Student Union and several teaching and learning spaces in Bangor.
Building work is expected to stat in May or June creating around 350 jobs. Presently demolition firm
The Bangor University-led Pontio project is now fully funded and will receive £12.5m from the European Regional Development Fund, and £15m from the Welsh government towards a cost of £40m.
A meet-the-contractor event is to be arranged to promote opportunities for vocational training during the construction period.
Mace is acting as project manager on the job.