The two-storey development, in the heart of the Clifton Campus, will feature a range of engineering, teaching and research spaces.
In terms of energy efficiency it has been designed to be in the top 10% of sustainable buildings in the country.
Work on the engineering facility, which will also include the creation of a new Institute of Industrial Digitalisation, Robotics and Automation is due to get under way in early June, with completion expected in time for the start of the 2019/2020 academic year.
The client team includes project manager Edge, quantity surveyor Gleeds, architect Maber and civil and structural engineer Curtins.
The contract for Henry Brothers follows completion last year of the £12.5m STEMLab project at Loughborough University.
It is the company’s first major Nottingham contract since setting up a Midlands office in 2015, and cements the £80m turnover firm’s position as a key player in the city.
Ian Taylor, managing director of Henry Brothers Midlands, said: “As a company, Henry Brothers has significant experience of partnering with universities to create inspiring buildings.
“Following the award-winning STEMLab project at Loughborough University, our team is currently on site with the same client delivering the £30m refurbishment of a 1960s building which houses science labs and teaching spaces.
“We are delighted to now be working with another major university in the East Midlands, Nottingham Trent University.”